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EMERGENCY MEDICINE (3)
ENT (5)
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GASTROINTESTINAL (29)
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MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
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PHARMACOLOGY (8)
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RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
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Mechanism of Action
Primary Target
Target Level
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
MOLNUPIRAVIR
3
Small molecule
Investigational
Unknown
Unknown
Severe Acute Respiratory Syndrome
Unknown
MOLNUPIRAVIR
×
Maximum Phase:
3
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C13H19N3O7
Molecular Weight:
329.31
AlogP:
-1.72
PSA:
146.37
HBD:
4.0
HBA:
#RotB:
4.0
Source:
SIVELESTAT SODIUM
3
Small molecule
Investigational
Unknown
Unknown
Severe Acute Respiratory Syndrome
Unknown
SIVELESTAT SODIUM
×
Maximum Phase:
3
First Approval:
None
UNII:
737RR8Y409
Molecule Type:
Small molecule
Molecular Formula:
C20H29N2NaO11S
Molecular Weight:
528.51
AlogP:
2.25
PSA:
138.87
HBD:
3.0
HBA:
#RotB:
7.0
Source:
NONIVAMIDE
3
Small molecule
Investigational
Unknown
Unknown
Low Back Pain
Unknown
NONIVAMIDE
×
Maximum Phase:
3
First Approval:
None
UNII:
S846B891OR
Molecule Type:
Small molecule
Molecular Formula:
C17H27NO3
Molecular Weight:
293.41
AlogP:
3.77
PSA:
58.56
HBD:
2.0
HBA:
#RotB:
10.0
Source:
LAFUTIDINE
3
Small molecule
Investigational
Unknown
Unknown
Gastritis; Stomach Ulcer; Gastroesophageal Reflux; Peptic Ulcer
Histamine H2 receptor antagonist
LAFUTIDINE
×
Maximum Phase:
3
First Approval:
None
UNII:
49S4O7ADLC
Molecule Type:
Small molecule
Molecular Formula:
C22H29N3O4S
Molecular Weight:
431.56
AlogP:
2.66
PSA:
84.67
HBD:
1.0
HBA:
#RotB:
11.0
Source:
CLAMOXYQUIN HYDROCHLORIDE
3
Small molecule
Investigational
Unknown
Unknown
Mastitis; Enterobacteriaceae Infections
Unknown
CLAMOXYQUIN HYDROCHLORIDE
×
Maximum Phase:
3
First Approval:
None
UNII:
SQ922M93PI
Molecule Type:
Small molecule
Molecular Formula:
C17H25Cl2N3O
Molecular Weight:
358.31
AlogP:
3.42
PSA:
48.39
HBD:
2.0
HBA:
#RotB:
8.0
Source:
TAK-536
3
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
TAK-536
×
Maximum Phase:
3
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZILSARTAN
3
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus; Diabetes Mellitus, Type 2; Essential Hypertension; Hypertension
Type-1 angiotensin II receptor antagonist
AZILSARTAN
×
Maximum Phase:
3
First Approval:
None
UNII:
F9NUX55P23
Molecule Type:
Small molecule
Molecular Formula:
C25H20N4O5
Molecular Weight:
456.46
AlogP:
4.6
PSA:
123.5
HBD:
2.0
HBA:
#RotB:
7.0
Source:
ABEXINOSTAT
3
Small molecule
Investigational
Unknown
Unknown
Hodgkin Disease; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Carcinoma, Renal Cell
Histone deacetylase inhibitor
ABEXINOSTAT
×
Maximum Phase:
3
First Approval:
None
UNII:
IYO470654U
Molecule Type:
Small molecule
Molecular Formula:
C21H23N3O5
Molecular Weight:
397.43
AlogP:
2.42
PSA:
104.04
HBD:
3.0
HBA:
#RotB:
8.0
Source:
PANTHENOL
3
Small molecule
Investigational
Unknown
Unknown
Common Cold; Diabetic Foot; Influenza, Human
Unknown
PANTHENOL
×
Maximum Phase:
3
First Approval:
None
UNII:
WV9CM0O67Z
Molecule Type:
Small molecule
Molecular Formula:
C9H19NO4
Molecular Weight:
205.25
AlogP:
-1.14
PSA:
89.79
HBD:
4.0
HBA:
#RotB:
6.0
Source:
TRANSCROCETINATE SODIUM
3
Small molecule
Investigational
Unknown
Unknown
Severe Acute Respiratory Syndrome; Glioblastoma
Unknown
TRANSCROCETINATE SODIUM
×
Maximum Phase:
3
First Approval:
None
UNII:
YP57637WMX
Molecule Type:
Small molecule
Molecular Formula:
C20H22Na2O4
Molecular Weight:
372.37
AlogP:
4.61
PSA:
74.6
HBD:
2.0
HBA:
#RotB:
8.0
Source:
OLESOXIME
3
Small molecule
Investigational
Unknown
Unknown
Multiple Sclerosis, Relapsing-Remitting; Muscular Atrophy, Spinal; Non-alcoholic Fatty Liver Disease; Peripheral Nervous System Diseases; Amyotrophic Lateral Sclerosis
Unknown
OLESOXIME
×
Maximum Phase:
3
First Approval:
None
UNII:
A6778U5IFY
Molecule Type:
Small molecule
Molecular Formula:
C27H45NO
Molecular Weight:
399.66
AlogP:
7.86
PSA:
32.59
HBD:
1.0
HBA:
#RotB:
5.0
Source:
MITOGUAZONE
3
Small molecule
Investigational
Unknown
Unknown
Lymphoma; Neoplasms
Unknown
MITOGUAZONE
×
Maximum Phase:
3
First Approval:
None
UNII:
OD5Q0L447W
Molecule Type:
Small molecule
Molecular Formula:
C5H12N8
Molecular Weight:
184.21
AlogP:
-2.11
PSA:
153.52
HBD:
4.0
HBA:
#RotB:
3.0
Source:
ALANINE
3
Small molecule
Investigational
Unknown
Unknown
Asthma; Glioma; Coronary Disease
Unknown
ALANINE
×
Maximum Phase:
3
First Approval:
None
UNII:
1FU7983T0U
Molecule Type:
Small molecule
Molecular Formula:
C3H7NO2
Molecular Weight:
89.09
AlogP:
-0.58
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
1.0
Source:
GALETERONE
3
Small molecule
Investigational
Unknown
Unknown
Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
Androgen Receptor antagonist
GALETERONE
×
Maximum Phase:
3
First Approval:
None
UNII:
WA33E149SW
Molecule Type:
Small molecule
Molecular Formula:
C26H32N2O
Molecular Weight:
388.56
AlogP:
5.81
PSA:
38.05
HBD:
1.0
HBA:
#RotB:
1.0
Source:
TYRAMINE
3
Small molecule
Investigational
Unknown
Unknown
Hypotension, Orthostatic; Orthostatic Intolerance; Parkinson Disease
Unknown
TYRAMINE
×
Maximum Phase:
3
First Approval:
None
UNII:
X8ZC7V0OX3
Molecule Type:
Small molecule
Molecular Formula:
C8H11NO
Molecular Weight:
137.18
AlogP:
0.89
PSA:
46.25
HBD:
2.0
HBA:
#RotB:
2.0
Source:
DABIGATRAN
3
Small molecule
Investigational
Unknown
Unknown
Ischemic Stroke; Renal Insufficiency; Respiratory Syncytial Virus Infections; CADASIL; Hemorrhage; Atrial Fibrillation; Hematoma; Stroke; Thromboembolism; Venous Thromboembolism; Wounds and Injuries
Thrombin inhibitor
DABIGATRAN
×
Maximum Phase:
3
First Approval:
None
UNII:
I0VM4M70GC
Molecule Type:
Small molecule
Molecular Formula:
C25H25N7O3
Molecular Weight:
471.52
AlogP:
2.99
PSA:
150.22
HBD:
4.0
HBA:
#RotB:
9.0
Source:
SIVELESTAT
3
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
SIVELESTAT
×
Maximum Phase:
3
First Approval:
None
UNII:
DWI62G0P59
Molecule Type:
Small molecule
Molecular Formula:
C20H22N2O7S
Molecular Weight:
434.47
AlogP:
2.25
PSA:
138.87
HBD:
3.0
HBA:
#RotB:
7.0
Source:
OXYCODEGOL
3
Small molecule
Investigational
Unknown
Unknown
Osteoarthritis, Knee; Chronic Pain; Low Back Pain
Mu opioid receptor agonist
OXYCODEGOL
×
Maximum Phase:
3
First Approval:
None
UNII:
J2WIV0JMML
Molecule Type:
Small molecule
Molecular Formula:
C31H49NO10
Molecular Weight:
595.73
AlogP:
1.59
PSA:
106.54
HBD:
1.0
HBA:
#RotB:
20.0
Source:
TOZADENANT
3
Small molecule
Investigational
Unknown
Unknown
Cocaine-Related Disorders; Liver Diseases; Parkinson Disease
Adenosine A2a receptor antagonist
TOZADENANT
×
Maximum Phase:
3
First Approval:
None
UNII:
D9K857J81I
Molecule Type:
Small molecule
Molecular Formula:
C19H26N4O4S
Molecular Weight:
406.51
AlogP:
2.52
PSA:
87.16
HBD:
2.0
HBA:
#RotB:
3.0
Source:
AMENAMEVIR
3
Small molecule
Investigational
Unknown
Unknown
Herpes Genitalis; Herpes Simplex; Herpes Zoster; Virus Diseases
Helicase primate complex inhibitor
AMENAMEVIR
×
Maximum Phase:
3
First Approval:
None
UNII:
94X46KW4AE
Molecule Type:
Small molecule
Molecular Formula:
C24H26N4O5S
Molecular Weight:
482.56
AlogP:
3.15
PSA:
122.47
HBD:
1.0
HBA:
#RotB:
6.0
Source:
BROTIZOLAM
3
Small molecule
Investigational
Unknown
Unknown
Anxiety; Dementia; Depressive Disorder; Schizophrenia; Sleep Initiation and Maintenance Disorders
Unknown
BROTIZOLAM
×
Maximum Phase:
3
First Approval:
None
UNII:
5XZM1R3DKF
Molecule Type:
Small molecule
Molecular Formula:
C15H10BrClN4S
Molecular Weight:
393.7
AlogP:
4.4
PSA:
43.07
HBD:
0.0
HBA:
#RotB:
1.0
Source:
ARBACLOFEN
3
Small molecule
Investigational
Unknown
Unknown
Child Development Disorders, Pervasive; Fragile X Syndrome; Muscle Spasticity
GABA-B receptor agonist
ARBACLOFEN
×
Maximum Phase:
3
First Approval:
None
UNII:
NYU6UTW25B
Molecule Type:
Small molecule
Molecular Formula:
C10H12ClNO2
Molecular Weight:
213.66
AlogP:
1.86
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
4.0
Source:
VADADUSTAT
3
Small molecule
Investigational
Unknown
Unknown
Liver Diseases; Renal Insufficiency, Chronic; Anemia
Egl nine homolog 1 inhibitor
VADADUSTAT
×
Maximum Phase:
3
First Approval:
None
UNII:
I60W9520VV
Molecule Type:
Small molecule
Molecular Formula:
C14H11ClN2O4
Molecular Weight:
306.71
AlogP:
1.92
PSA:
99.52
HBD:
3.0
HBA:
#RotB:
4.0
Source:
PERFLUBUTANE
3
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PERFLUBUTANE
×
Maximum Phase:
3
First Approval:
None
UNII:
SE4TWR0K2C
Molecule Type:
Small molecule
Molecular Formula:
C4F10
Molecular Weight:
238.02
AlogP:
3.38
PSA:
0.0
HBD:
0.0
HBA:
#RotB:
1.0
Source:
LIPEGFILGRASTIM
3
Small molecule
Investigational
Unknown
Unknown
Sarcoma, Ewing; Lymphoma
Granulocyte colony stimulating factor receptor agonist
LIPEGFILGRASTIM
×
Maximum Phase:
3
First Approval:
None
UNII:
4AWF0N6QV3
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CADAZOLID
3
Small molecule
Investigational
Unknown
Unknown
Clostridium Infections
Bacterial 70S ribosome inhibitor
CADAZOLID
×
Maximum Phase:
3
First Approval:
None
UNII:
2OEA2UN10Y
Molecule Type:
Small molecule
Molecular Formula:
C29H29F2N3O8
Molecular Weight:
585.56
AlogP:
3.04
PSA:
141.77
HBD:
3.0
HBA:
#RotB:
8.0
Source:
PYRITINOL
3
Small molecule
Investigational
Unknown
Unknown
Anxiety; Attention Deficit Disorder with Hyperactivity; Dementia; Depressive Disorder; Schizophrenia
Unknown
PYRITINOL
×
Maximum Phase:
3
First Approval:
None
UNII:
AK5Q5FZH2R
Molecule Type:
Small molecule
Molecular Formula:
C16H20N2O4S2
Molecular Weight:
368.48
AlogP:
2.57
PSA:
106.7
HBD:
4.0
HBA:
#RotB:
7.0
Source:
OXETHAZAINE
3
Small molecule
Investigational
Unknown
Unknown
Hemorrhoids
Unknown
OXETHAZAINE
×
Maximum Phase:
3
First Approval:
None
UNII:
IP8QT76V17
Molecule Type:
Small molecule
Molecular Formula:
C28H41N3O3
Molecular Weight:
467.65
AlogP:
3.24
PSA:
64.09
HBD:
1.0
HBA:
#RotB:
12.0
Source:
EVOCALCET
3
Small molecule
Investigational
Unknown
Unknown
Hyperparathyroidism; Hyperparathyroidism, Secondary
Calcium sensing receptor positive allosteric modulator
EVOCALCET
×
Maximum Phase:
3
First Approval:
None
UNII:
E58MLH082P
Molecule Type:
Small molecule
Molecular Formula:
C24H26N2O2
Molecular Weight:
374.48
AlogP:
4.4
PSA:
52.57
HBD:
2.0
HBA:
#RotB:
6.0
Source:
APLAVIROC
3
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
APLAVIROC
×
Maximum Phase:
3
First Approval:
None
UNII:
98B425P30V
Molecule Type:
Small molecule
Molecular Formula:
C33H43N3O6
Molecular Weight:
577.72
AlogP:
4.58
PSA:
119.41
HBD:
3.0
HBA:
#RotB:
10.0
Source:
PYRIDOXAL
3
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PYRIDOXAL
×
Maximum Phase:
3
First Approval:
None
UNII:
3THM379K8A
Molecule Type:
Small molecule
Molecular Formula:
C8H9NO3
Molecular Weight:
167.16
AlogP:
0.4
PSA:
70.42
HBD:
2.0
HBA:
#RotB:
2.0
Source:
PRULIFLOXACIN
3
Small molecule
Investigational
Unknown
Unknown
Prostatitis; Bacterial Infections; Bronchitis, Chronic; Gastroenteritis; Urinary Tract Infections
Bacterial DNA gyrase inhibitor
PRULIFLOXACIN
×
Maximum Phase:
3
First Approval:
None
UNII:
J42298IESW
Molecule Type:
Small molecule
Molecular Formula:
C21H20FN3O6S
Molecular Weight:
461.47
AlogP:
2.64
PSA:
109.13
HBD:
1.0
HBA:
#RotB:
4.0
Source:
MEDETOMIDINE
3
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MEDETOMIDINE
×
Maximum Phase:
3
First Approval:
None
UNII:
MR15E85MQM
Molecule Type:
Small molecule
Molecular Formula:
C13H16N2
Molecular Weight:
200.28
AlogP:
3.18
PSA:
28.68
HBD:
1.0
HBA:
#RotB:
2.0
Source:
POLYFEROSE
3
Small molecule
Investigational
Unknown
Unknown
Anemia, Iron-Deficiency
Unknown
POLYFEROSE
×
Maximum Phase:
3
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VINTAFOLIDE
3
Small molecule
Investigational
Unknown
Unknown
Adenocarcinoma of Lung; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms; Ovarian Neoplasms
Folate receptor alpha binding agent
VINTAFOLIDE
×
Maximum Phase:
3
First Approval:
None
UNII:
36O410ZD4I
Molecule Type:
Small molecule
Molecular Formula:
C86H109N21O26S2
Molecular Weight:
1917.07
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
1
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158
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PSA