Display Options:
Total: 10647
Small molecule
Approved
Unknown
Unknown
Hypersensitivity
Histamine H1 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Unknown
Histamine H1 receptor antagonist
Enzyme
Approved
OTHER
UNKNOWN
Granuloma, Lethal Midline; Leukemia; Leukemia, Biphenotypic, Acute; Lymphohistiocytosis, Hemophagocytic; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Asparagine hydrolytic enzyme
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Enzyme
Approved
OTHER
UNKNOWN
Leukemia, Biphenotypic, Acute; Leukemia, Lymphoid; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Leukemia; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Myeloproliferative Disorders; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Myeloid; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Asparagine hydrolytic enzyme
Small molecule
Approved
Unknown
Unknown
Fatty Liver; Cystic Fibrosis; HIV Infections; Cystinosis; Eye Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Wet Macular Degeneration; Glaucoma, Open-Angle; Ocular Hypertension; Glaucoma
Unknown
Protein
Approved
Unknown
Unknown
Unknown
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Migraine Disorders; Neuromyelitis Optica; Rhinitis; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Eczema; Pemphigus; Pruritus; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Hypersensitivity
Unknown
Small molecule
Approved
OTHER
INJECTION
Unknown
Diagnostic agent
Small molecule
Unknown
Unknown
Unknown
Alcoholism
Opioid receptors; mu/kappa/delta antagonist
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Hypotension, Orthostatic; Nesidioblastosis; Obesity; Aging; Non-alcoholic Fatty Liver Disease; Atherosclerosis; Coronary Disease; Diabetes, Gestational; Hypercholesterolemia; Hypertension; Metabolic Diseases; Metabolic Syndrome; Diabetes Mellitus; Diabetes Mellitus, Type 2
Maltase-glucoamylase inhibitor
Small molecule
Approved
Unknown
Unknown
Peripheral Arterial Disease; Aging; Constriction, Pathologic; Diabetes Mellitus, Type 2; Melanoma; Osteoarthritis, Knee; Osteosarcoma; Wounds and Injuries; Anemia, Sickle Cell; Cardiomyopathy, Hypertrophic; Cystic Fibrosis; Diabetes Mellitus, Type 1; Glomerulosclerosis, Focal Segmental; HIV Infections; Idiopathic Pulmonary Fibrosis; Inflammation; Pancreatic Neoplasms; Respiratory Distress Syndrome; Sarcopenia; Stress Disorders, Post-Traumatic; Diabetic Nephropathies; Essential Hypertension; Glioblastoma; Glomerulonephritis, IGA; Heart Failure; Hyperoxaluria, Primary; Hypertension; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Kidney Diseases; Marfan Syndrome; Non-alcoholic Fatty Liver Disease; Proteinuria; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases
Unknown
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
INJECTION
Chordoma; Fanconi Anemia; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myeloproliferative Disorders; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Retinoblastoma; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Squamous Cell; Hepatoblastoma; Lung Neoplasms; Multiple Myeloma; Nasopharyngeal Neoplasms; Peripheral Nervous System Diseases; Trigeminal Neuralgia; Head and Neck Neoplasms; Ovarian Neoplasms; Xerostomia
Reactive metabolite scavenging agent
Small molecule
Approved
IMMUNE SYSTEM
ORAL
Hypertension, Pulmonary; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; HIV Infections; Virus Diseases
Human immunodeficiency virus type 1 protease inhibitor
Small molecule
Approved
Unknown
Unknown
Kidney Diseases; Opioid-Related Disorders; Dermatitis, Atopic; Gambling; Non-alcoholic Fatty Liver Disease; Smoking Cessation; Alcoholism
Unknown
Small molecule
Approved
Unknown
Unknown
Arrhythmias, Cardiac
Unknown
Small molecule
Approved
Unknown
Unknown
Liver Cirrhosis, Biliary; Cardiovascular Diseases
Unknown
Small molecule
Approved
OTHER
ORAL
Fallopian Tube Neoplasms; Gynecomastia; Ovarian Neoplasms; Peritoneal Neoplasms; Puberty, Precocious; Salivary Gland Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Carcinoma; Neoplasms
Androgen Receptor antagonist
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Breast Neoplasms; Stress Disorders, Post-Traumatic; Alzheimer Disease; Bipolar Disorder; Cerebellar Ataxia; Child Development Disorders, Pervasive; Depressive Disorder; Depressive Disorder, Major; Melanoma; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Atrophy, Spinal; Obsessive-Compulsive Disorder; Peripheral Nervous System Diseases; Spinal Cord Injuries; Huntington Disease; Multiple System Atrophy; Spinal Cord Diseases; Spinocerebellar Ataxias; Supranuclear Palsy, Progressive; Amyotrophic Lateral Sclerosis
Sodium channel alpha subunit blocker
Small molecule
Approved
Unknown
Unknown
Heart Defects, Congenital; Neoplasms; Osteosarcoma; Ganglioneuroblastoma; Leukemia, Myeloid, Acute; Multiple Sclerosis; Myelodysplastic Syndromes; Neuroblastoma; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Hepatoblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma
DNA topoisomerase II inhibitor
Small molecule
Approved
CANCER; OTHER
ORAL
Hypertension; Aging; Endometrial Neoplasms; Kallmann Syndrome; Anovulation; Breast Neoplasms, Male; Carcinoma; Endometriosis; Fibrous Dysplasia, Polyostotic; Hypertension, Pulmonary; Hypogonadism; Hypopituitarism; Metabolic Syndrome; Ovarian Neoplasms; Peritoneal Neoplasms; Puberty, Precocious; Triple Negative Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Gynecomastia; Breast Neoplasms; Neoplasms
Cytochrome P450 19A1 inhibitor
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Carcinoma, Squamous Cell; Depressive Disorder, Major; Hip Fractures; Neuralgia; Osteoarthritis; Rotator Cuff Injuries; Substance Withdrawal Syndrome; Wounds and Injuries; Abdominal Pain; Chronic Pain; Diabetic Neuropathies; Fibromyalgia; Low Back Pain; Opioid-Related Disorders; Osteoarthritis, Knee; Pain
Unknown
Small molecule
Unknown
Unknown
Unknown
Small Cell Lung Carcinoma; Carcinoma, Non-Small-Cell Lung; Urinary Bladder Neoplasms; Brain Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Bile Duct Neoplasms; Central Nervous System Neoplasms; Gallbladder Neoplasms; Klatskin Tumor; Neoplasms
DNA inhibitor
Small molecule
Unknown
Unknown
Unknown
Hypertension
Angiotensin-converting enzyme inhibitor
Small molecule
Approved
Unknown
Unknown
Ependymoma; Glioma; Infectious Mononucleosis; Lung Neoplasms; Prostatic Neoplasms; Astrocytoma; Bipolar Disorder; Cytomegalovirus Infections; Glioblastoma; Hepatitis C, Chronic; Leukemia, Lymphocytic, Chronic, B-Cell; Neuralgia, Postherpetic; Psychotic Disorders; Pulmonary Disease, Chronic Obstructive; Schizophrenia; Stomatitis, Herpetic; Waldenstrom Macroglobulinemia; Encephalitis; Herpes Simplex; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Herpes Genitalis; Herpes Labialis; Herpes Zoster; Virus Diseases
Unknown
Small molecule
Approved
OTHER
INJECTION
Unknown
Diagnostic agent
Small molecule
Unknown
Unknown
Unknown
Osteomyelitis; Pyelonephritis; Bacterial Infections; Bronchitis, Chronic; Otitis Media
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
CARDIOVASCULAR; OTHER
INJECTION
Unknown
HERG blocker
Small molecule
Unknown
Unknown
Unknown
Colorectal Neoplasms; Heart Diseases; Inflammation; Postoperative Complications; Acute Kidney Injury; Alcohol-Related Disorders; Brain Injuries; Breast Neoplasms; Delirium; Hernias, Diaphragmatic, Congenital; Lung Neoplasms; Myocardial Infarction; Obesity; Obesity, Morbid; Opioid-Related Disorders; Renal Insufficiency; Shock, Septic; Subarachnoid Hemorrhage; Tonsillitis; Back Pain; Coronary Disease; Esophageal Neoplasms; Fluoride Poisoning; Intracranial Aneurysm; Neoplasms; Pain; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Insufficiency; Severe Acute Respiratory Syndrome
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
GASTROINTESTINAL; OTHER
INTRAVENOUS; ORAL
Cystic Fibrosis; Laryngopharyngeal Reflux; Neoplasms; Pain; Endometrial Neoplasms; Eosinophilic Esophagitis; Leukemia, Lymphocytic, Chronic, B-Cell; Premature Birth; Pseudomyxoma Peritonei; Rectal Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Diabetes Mellitus, Type 1; Duodenal Ulcer; Esophagitis, Peptic; Gastritis; Gout; Helicobacter Infections; Idiopathic Pulmonary Fibrosis; Lymphoma; Osteoarthritis; Gastroesophageal Reflux; Peptic Ulcer; Stomach Ulcer
Potassium-transporting ATPase inhibitor
Small molecule
Unknown
Unknown
Unknown
Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Central Nervous System Neoplasms; Inflammatory Breast Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Lymphoma; Sarcoma; Breast Neoplasms; Cardiomyopathies
Unknown
Small molecule
Approved
OTHER
ORAL
Cardiovascular Diseases; Hypertension
Voltage-gated L-type calcium channel blocker
Small molecule
Unknown
Unknown
Unknown
Pre-Eclampsia; Pancreatic Neoplasms; Carcinoma, Pancreatic Ductal; Eosinophilic Esophagitis; Non-alcoholic Fatty Liver Disease; Essential Hypertension; Hypertrophy, Left Ventricular; Marfan Syndrome; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Proteinuria; Stroke
Type-1 angiotensin II receptor antagonist
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown