DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Small molecule Approved Unknown Unknown Hypersensitivity Histamine H1 receptor antagonist


Small molecule Approved Unknown Unknown Unknown Histamine H1 receptor antagonist


Small molecule Approved Unknown Unknown Unknown Unknown


Enzyme Approved OTHER UNKNOWN Granuloma, Lethal Midline; Leukemia; Leukemia, Biphenotypic, Acute; Lymphohistiocytosis, Hemophagocytic; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma Asparagine hydrolytic enzyme


Small molecule Approved Unknown Unknown Wet Macular Degeneration; Glaucoma, Open-Angle; Ocular Hypertension; Glaucoma Unknown


Small molecule Approved Unknown Unknown Fatty Liver; Cystic Fibrosis; HIV Infections; Cystinosis; Eye Diseases Unknown


Protein Approved Unknown Unknown Unknown Diagnostic agent


Enzyme Approved OTHER UNKNOWN Leukemia, Biphenotypic, Acute; Leukemia, Lymphoid; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Leukemia; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Myeloproliferative Disorders; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Myeloid; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma Asparagine hydrolytic enzyme

Enzyme

Approved

OTHER

UNKNOWN

Leukemia, Biphenotypic, Acute; Leukemia, Lymphoid; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Leukemia; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Myeloproliferative Disorders; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Myeloid; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma

Asparagine hydrolytic enzyme


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent


Small molecule Approved Unknown Unknown Migraine Disorders; Neuromyelitis Optica; Rhinitis; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Eczema; Pemphigus; Pruritus; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Hypersensitivity Unknown


Small molecule Unknown Unknown Unknown Alcoholism Opioid receptors; mu/kappa/delta antagonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Hypotension, Orthostatic; Nesidioblastosis; Obesity; Aging; Non-alcoholic Fatty Liver Disease; Atherosclerosis; Coronary Disease; Diabetes, Gestational; Hypercholesterolemia; Hypertension; Metabolic Diseases; Metabolic Syndrome; Diabetes Mellitus; Diabetes Mellitus, Type 2 Maltase-glucoamylase inhibitor


Small molecule Approved Unknown Unknown Peripheral Arterial Disease; Aging; Constriction, Pathologic; Diabetes Mellitus, Type 2; Melanoma; Osteoarthritis, Knee; Osteosarcoma; Wounds and Injuries; Anemia, Sickle Cell; Cardiomyopathy, Hypertrophic; Cystic Fibrosis; Diabetes Mellitus, Type 1; Glomerulosclerosis, Focal Segmental; HIV Infections; Idiopathic Pulmonary Fibrosis; Inflammation; Pancreatic Neoplasms; Respiratory Distress Syndrome; Sarcopenia; Stress Disorders, Post-Traumatic; Diabetic Nephropathies; Essential Hypertension; Glioblastoma; Glomerulonephritis, IGA; Heart Failure; Hyperoxaluria, Primary; Hypertension; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Kidney Diseases; Marfan Syndrome; Non-alcoholic Fatty Liver Disease; Proteinuria; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases Unknown

Small molecule

Approved

Unknown

Peripheral Arterial Disease; Aging; Constriction, Pathologic; Diabetes Mellitus, Type 2; Melanoma; Osteoarthritis, Knee; Osteosarcoma; Wounds and Injuries; Anemia, Sickle Cell; Cardiomyopathy, Hypertrophic; Cystic Fibrosis; Diabetes Mellitus, Type 1; Glomerulosclerosis, Focal Segmental; HIV Infections; Idiopathic Pulmonary Fibrosis; Inflammation; Pancreatic Neoplasms; Respiratory Distress Syndrome; Sarcopenia; Stress Disorders, Post-Traumatic; Diabetic Nephropathies; Essential Hypertension; Glioblastoma; Glomerulonephritis, IGA; Heart Failure; Hyperoxaluria, Primary; Hypertension; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Kidney Diseases; Marfan Syndrome; Non-alcoholic Fatty Liver Disease; Proteinuria; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases

Unknown


Small molecule Approved IMMUNE SYSTEM ORAL Hypertension, Pulmonary; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 protease inhibitor


Small molecule Approved Unknown Unknown Kidney Diseases; Opioid-Related Disorders; Dermatitis, Atopic; Gambling; Non-alcoholic Fatty Liver Disease; Smoking Cessation; Alcoholism Unknown


Small molecule Approved Unknown Unknown Liver Cirrhosis, Biliary; Cardiovascular Diseases Unknown


Small molecule Approved OTHER ORAL Fallopian Tube Neoplasms; Gynecomastia; Ovarian Neoplasms; Peritoneal Neoplasms; Puberty, Precocious; Salivary Gland Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Carcinoma; Neoplasms Androgen Receptor antagonist


Small molecule Approved Unknown Unknown Arrhythmias, Cardiac Unknown


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Breast Neoplasms; Stress Disorders, Post-Traumatic; Alzheimer Disease; Bipolar Disorder; Cerebellar Ataxia; Child Development Disorders, Pervasive; Depressive Disorder; Depressive Disorder, Major; Melanoma; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Atrophy, Spinal; Obsessive-Compulsive Disorder; Peripheral Nervous System Diseases; Spinal Cord Injuries; Huntington Disease; Multiple System Atrophy; Spinal Cord Diseases; Spinocerebellar Ataxias; Supranuclear Palsy, Progressive; Amyotrophic Lateral Sclerosis Sodium channel alpha subunit blocker

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Breast Neoplasms; Stress Disorders, Post-Traumatic; Alzheimer Disease; Bipolar Disorder; Cerebellar Ataxia; Child Development Disorders, Pervasive; Depressive Disorder; Depressive Disorder, Major; Melanoma; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Atrophy, Spinal; Obsessive-Compulsive Disorder; Peripheral Nervous System Diseases; Spinal Cord Injuries; Huntington Disease; Multiple System Atrophy; Spinal Cord Diseases; Spinocerebellar Ataxias; Supranuclear Palsy, Progressive; Amyotrophic Lateral Sclerosis

Sodium channel alpha subunit blocker


Small molecule Approved CANCER; OTHER ORAL Hypertension; Aging; Endometrial Neoplasms; Kallmann Syndrome; Anovulation; Breast Neoplasms, Male; Carcinoma; Endometriosis; Fibrous Dysplasia, Polyostotic; Hypertension, Pulmonary; Hypogonadism; Hypopituitarism; Metabolic Syndrome; Ovarian Neoplasms; Peritoneal Neoplasms; Puberty, Precocious; Triple Negative Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Gynecomastia; Breast Neoplasms; Neoplasms Cytochrome P450 19A1 inhibitor

Small molecule

Approved

CANCER; OTHER

ORAL

Hypertension; Aging; Endometrial Neoplasms; Kallmann Syndrome; Anovulation; Breast Neoplasms, Male; Carcinoma; Endometriosis; Fibrous Dysplasia, Polyostotic; Hypertension, Pulmonary; Hypogonadism; Hypopituitarism; Metabolic Syndrome; Ovarian Neoplasms; Peritoneal Neoplasms; Puberty, Precocious; Triple Negative Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Gynecomastia; Breast Neoplasms; Neoplasms

Cytochrome P450 19A1 inhibitor


Small molecule Unknown Unknown Unknown Hypertension Angiotensin-converting enzyme inhibitor


Small molecule Unknown Unknown Unknown Small Cell Lung Carcinoma; Carcinoma, Non-Small-Cell Lung; Urinary Bladder Neoplasms; Brain Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Bile Duct Neoplasms; Central Nervous System Neoplasms; Gallbladder Neoplasms; Klatskin Tumor; Neoplasms DNA inhibitor


Small molecule Approved Unknown Unknown Breast Neoplasms; Carcinoma, Squamous Cell; Depressive Disorder, Major; Hip Fractures; Neuralgia; Osteoarthritis; Rotator Cuff Injuries; Substance Withdrawal Syndrome; Wounds and Injuries; Abdominal Pain; Chronic Pain; Diabetic Neuropathies; Fibromyalgia; Low Back Pain; Opioid-Related Disorders; Osteoarthritis, Knee; Pain Unknown


Small molecule Approved OTHER ORAL Glioblastoma; Vascular Diseases; Breast Neoplasms; Cocaine-Related Disorders; Epilepsy; Esophageal and Gastric Varices; Hypertension, Pulmonary; Hypoglycemia; Kidney Diseases; Lymphoma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Tobacco Use Disorder; Atherosclerosis; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Portal; Hypertrophy, Left Ventricular; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Multiple Myeloma; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left Adrenergic receptor alpha-1 antagonist

Small molecule

Approved

OTHER

ORAL

Glioblastoma; Vascular Diseases; Breast Neoplasms; Cocaine-Related Disorders; Epilepsy; Esophageal and Gastric Varices; Hypertension, Pulmonary; Hypoglycemia; Kidney Diseases; Lymphoma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Tobacco Use Disorder; Atherosclerosis; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Portal; Hypertrophy, Left Ventricular; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Multiple Myeloma; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left

Adrenergic receptor alpha-1 antagonist


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent


Small molecule Unknown Unknown Unknown Osteomyelitis; Pyelonephritis; Bacterial Infections; Bronchitis, Chronic; Otitis Media Bacterial penicillin-binding protein inhibitor


Small molecule Approved CARDIOVASCULAR; OTHER INJECTION Unknown HERG blocker

Small molecule

Approved

GASTROINTESTINAL; OTHER

INTRAVENOUS; ORAL

Cystic Fibrosis; Laryngopharyngeal Reflux; Neoplasms; Pain; Endometrial Neoplasms; Eosinophilic Esophagitis; Leukemia, Lymphocytic, Chronic, B-Cell; Premature Birth; Pseudomyxoma Peritonei; Rectal Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Diabetes Mellitus, Type 1; Duodenal Ulcer; Esophagitis, Peptic; Gastritis; Gout; Helicobacter Infections; Idiopathic Pulmonary Fibrosis; Lymphoma; Osteoarthritis; Gastroesophageal Reflux; Peptic Ulcer; Stomach Ulcer

Potassium-transporting ATPase inhibitor


Small molecule Unknown Unknown Unknown Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Central Nervous System Neoplasms; Inflammatory Breast Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Lymphoma; Sarcoma; Breast Neoplasms; Cardiomyopathies Unknown

Small molecule

Unknown

Colorectal Neoplasms; Heart Diseases; Inflammation; Postoperative Complications; Acute Kidney Injury; Alcohol-Related Disorders; Brain Injuries; Breast Neoplasms; Delirium; Hernias, Diaphragmatic, Congenital; Lung Neoplasms; Myocardial Infarction; Obesity; Obesity, Morbid; Opioid-Related Disorders; Renal Insufficiency; Shock, Septic; Subarachnoid Hemorrhage; Tonsillitis; Back Pain; Coronary Disease; Esophageal Neoplasms; Fluoride Poisoning; Intracranial Aneurysm; Neoplasms; Pain; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Insufficiency; Severe Acute Respiratory Syndrome

GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved OTHER ORAL Cardiovascular Diseases; Hypertension Voltage-gated L-type calcium channel blocker


Small molecule Approved DERMATOLOGY; OTHER TOPICAL Dermatitis, Perioral; Dermatitis, Seborrheic; Acne Vulgaris; Erythema; Rosacea Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Unknown Unknown Unknown Pre-Eclampsia; Pancreatic Neoplasms; Carcinoma, Pancreatic Ductal; Eosinophilic Esophagitis; Non-alcoholic Fatty Liver Disease; Essential Hypertension; Hypertrophy, Left Ventricular; Marfan Syndrome; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Proteinuria; Stroke Type-1 angiotensin II receptor antagonist


Small molecule Approved Unknown Unknown Heart Defects, Congenital; Neoplasms; Osteosarcoma; Ganglioneuroblastoma; Leukemia, Myeloid, Acute; Multiple Sclerosis; Myelodysplastic Syndromes; Neuroblastoma; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Hepatoblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma DNA topoisomerase II inhibitor